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http://repository.tma.uz/xmlui/handle/1/1577| Title: | Allelic polymorphism of the il-1β (rs1143627) gene in patients with immune thrombocy th immune thrombocytopenia. |
| Authors: | Hamid Y. Karimov , Dilfuza S. Matkarimova ,Kodirjon T. Boboev . |
| Keywords: | immune thrombocytopenia, IL-1β (rs1143627) gene polymorphism, allele, genotype, association, risk of development. |
| Issue Date: | 2021 |
| Publisher: | Central asian journal of medicine |
| Abstract: | Purpose of the study. To study the features of the frequency distribution of alleles and genotypes of IL-1β (rs1143627) gene polymorphism, its role in the development of ITP in people of the Uzbek ethnic group. Material and methods: The study included 89 patients with ITP (median age - 41 ± 1.7 years) (main group) who were admitted for examination by the RSPMCH in the period from 2012 to 2018. Detection of IL-1β (rs1143627) polymorphism was carried out by SNP-PCR. Results and its discussion. Carriage of the IL-1β gene polymorphism (rs1143627) is not associated with the risk of developing immune thrombocytopenia. |
| URI: | http://repository.tma.uz/xmlui/handle/1/1577 |
| Appears in Collections: | Thesis, Articles |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 1.Matkarimova D.S. Central Asian Journal 2021 №1.pdf | Allelic polymorphism of the il-1β (rs1143627) gene in patients with immune thrombocy th immune thrombocytopenia. | 300.36 kB | Adobe PDF | View/Open |
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