Please use this identifier to cite or link to this item: http://repository.tma.uz/xmlui/handle/1/1993
Title: The role of molecular biological and immunological markers in the diagnosis and treatment of patients with oropharyngeal cancer
Other Titles: The role of molecular biological and immunological markers in the diagnosis and treatment of patients with oropharyngeal cancer
Authors: Ermatov, Nizom Djumakulovich
Ganiev, Abduavaz Abdulahatovich
Nabieva, Umida Pulatjanovna
Samigova, Nargiz Raimovna
Khalmatova, Matlyuba Artykovna
Alimukhamedov, Dilshod Shavkatovich
Keywords: oncology, dentistry, cancer of the oral cavity and oropharynx, diagnostics, Epstein-Barr virus, circulating immune complexes, prognosis.
Issue Date: 2022
Publisher: "Journal of Positive School Psychology", Turkiye
Abstract: It has been established that small-sized circulating immune complexes have great pathological potential, while a high level of small circulating immune complexes shows an active fight of immunity against virus antigens, on the one hand, and on the other hand, is associated with a violation of the mechanisms of virus elimination, which plays a significant role in the formation and maintaining the malignant process. All this contributes to the violation of immune regulation, triggering the mechanisms of carcinogenesis with the development of the disease. Thus, the combined determination of the level of VEGF, the CD95+ apoptosis marker, and the IRI immunoregulation index in complex clinical cases improves the diagnosis of OPR and allows timely prediction of a more severe course of oropharyngeal cancer to avoid unnecessary biopsies or sectoral resections.
URI: http://repository.tma.uz/xmlui/handle/1/1993
Appears in Collections:Thesis, Articles

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