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http://repository.tma.uz/xmlui/handle/1/491| Title: | Study of genotype frequency distribution polymorphic marker of T-786C of enos3 gene in diabetic nephropathy in patients with CD2 type |
| Authors: | Jabbarov Ozimboy Otakhonovich, Karimov Hamid Yakubovich, Daminov Botir Turgunpulatovich, Boboev Kodirjon Tuhtaboevich |
| Keywords: | Keywords: diabetic nephropathy, diabetes mellitus, nitrogen oxide synthase, endothelin-1, gene, polymorphism, allele, genotype. |
| Issue Date: | 2019 |
| Publisher: | Tashkent |
| Abstract: | This article presents the results of a study of 129 patients with 2-type diabetes and 110 healthy people to determine whether polymorphic markers T-786C of the ENOS3 gene are related to the development of diabetic nephropathy (DN). Patients in the main group: 65 patients with duration of disease up to 10 years, without diabetic nephropathy (33 patients) and with diabetic nephropathy (32 patients), 64 patients with diabetes lasting more than 10-20 years, without diabetic nephropathy (31 patients) and diabetic nephropathy (33 patients). Genotyping was performed by polymerase chain reaction method. The study showed that the association of Callele C and ENOS3 gene genotype play a role in the development of diabetic nephropathy in patients with type 2 diabetes mellitus in the studied Uzbek nation. |
| URI: | http://repository.tma.uz/xmlui/handle/1/491 |
| Appears in Collections: | Thesis, Articles |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 34..pdf | Study of genotype frequency distribution polymorphic marker of T-786C of enos3 gene in diabetic nephropathy in patients with CD2 type | 209.05 kB | Adobe PDF | View/Open |
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