РЕГУЛЯЦИЯ АТФ-ЗАВИСИМОГО К+  КАНАЛ МИТОХОНДРИЙ ПЕЧЕНИ ПРИ ДЕЙСТВИЯ  ПОЛИФЕНОЛОВ

Please use this identifier to cite or link to this item: http://repository.tma.uz/xmlui/handle/1/5759

Title:	РЕГУЛЯЦИЯ АТФ-ЗАВИСИМОГО К+ КАНАЛ МИТОХОНДРИЙ ПЕЧЕНИ ПРИ ДЕЙСТВИЯ ПОЛИФЕНОЛОВ
Authors:	Abdullayeva, G.T., Abdullayeva, M.T., Asrarov, M.I Kurbanova, M.A.
Keywords:	liver, mitoK+ ATF-chanal, dysfunction, rutan, getasan, euforbin, correction, mitochondria. печень, мито К+ АТФ –канал, дисфункция, рутан, гетасан, эуфорбин, коррекция, митохондрии
Issue Date:	2022
Publisher:	Вестник ТМА №8
Series/Report no.:	UDK:577.121.7;
Abstract:	Objective: To study the effect of polyphenols rutan, getazan and euphorbin on the mitotic K+ATP channel of rat liver. Materials and methods: Conductivity of ATP-dependent K+ channels (0.3-0.4 mg/ml) in rat liver mitochondria was determined by changes in optical density at a wavelength of 540 nm in 3-ml cells. Results: The influence of the polyphenols rutan, getazan and euphorbin on the mitotic K+ATP channel in rats was studied. The results showed that the polyphenols rutan, getasan, and euphorbin activated mitochondrial channels in rats. Conclusion: The polyphenols of rutan, getasan and euphorbin have the ability to activate the mito K+ATP channel, which means that in the future they can be used to develop new drugs for cardioprotection and hypoxia.
URI:	http://repository.tma.uz/xmlui/handle/1/5759
ISSN:	2181-7812
Appears in Collections:	Thesis, Articles

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