Genetic aspects of reactive arthritis

Abstract

Reactive arthritis is one of the most common chronic inflammatory diseases of the joints. Patients with reactive arthritis make up about 10% of patients in rheumatological hospitals, and in the chronic form of the disease, a significant loss of the functional abilities of the joints and the occurrence of severe complications can develop, which leads to disability of patients. Interest in reactive arthritis is also associated with the fact that a number of patients, especially when the process is chronic, develop destructive processes in the joints up to ankylosing. The development of destruction of the joints and spine in patients with reactive arthritis, in turn, adversely affects the quality of life of patients, especially in young people, as well as a decrease in their ability to work and an increase in morbidity remain an urgent problem.