Abstract:
to study in detail the pathogenetic aspects of COVID-19, which will
allow us to understand the genesis of the development of the disease, as well as their
complications. This will improve the medical care provided to this category of
patients. The relationship between triggering the release of pro-inflammatory
cytokines with the development of infiltration in endothelial cells, microvascular
dysfunction, and an increase in respiratory failure is presented. Based on the literature
review data, the article describes the genesis of the trigger development of respiratory
pathology, as well as multiple organ failure, which contribute to the progression of
COVID-19.