Please use this identifier to cite or link to this item: http://repository.tma.uz/xmlui/handle/1/1037
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dc.contributor.authorNazarova, Nigora-
dc.contributor.authorUmarova, Gulrukh-
dc.contributor.authorVaiman, Michael-
dc.date.accessioned2021-12-27T06:10:23Z-
dc.date.available2021-12-27T06:10:23Z-
dc.date.issued2021-03-28-
dc.identifier.citationBackground: We compared the curettage/bone grafting and the curettage/bone graft substitutes surgical tech niques in their relation to functional outcomes, oncologic outcome (recurrence, malignant transformation), the rate of postsurgical complications, durations of surgery and of postsurgical immobilization for hand-localized cases of solitary and multiple enchondromas. Methods: The current prospective randomized trial analyzed 200 adult patients (2012–2017) with enchondroma who underwent surgical intervention. The cases were randomly divided into Group 1 (n = 100; F 56, M 44) for surgeries with curettage and autogenous bone grafting, and Group 2 (n = 100; F 55, M 45) for surgeries with curettage and bone graft substitutes. The placebo control Group 3 consisted of cases operated by curettage only (n = 56; F 31, M 25). The follow-up period was set at 30 months. Results: The duration of surgery was 51 ± 4 min in Group 1 and 27 ± 1 min in Group 2 (p = 0.008). In Group 1, the rate of recurrence was 6% against 1% in Group 2 (p = 0.005). No other statistically significant differences in postsurgical outcomes between three involved groups were noted. Conclusion: In cases of enchondroma of the hand, postsurgical functional outcomes, the rate of postsurgical complications, the duration of immobilization, and the time to complete recovery are not influenced by the type of chosen grafting material. The implementation of HAp-collagen bone substitutes in granules instead of autogenous bone grafting reduces the duration of surgery. The implementation of autogenous bone grafting may increase the rate of tumor recurrence.en_US
dc.identifier.issn2021.101565-
dc.identifier.urihttp://repository.tma.uz/xmlui/handle/1/1037-
dc.description.abstractBackground: We compared the curettage/bone grafting and the curettage/bone graft substitutes surgical tech niques in their relation to functional outcomes, oncologic outcome (recurrence, malignant transformation), the rate of postsurgical complications, durations of surgery and of postsurgical immobilization for hand-localized cases of solitary and multiple enchondromas. Methods: The current prospective randomized trial analyzed 200 adult patients (2012–2017) with enchondroma who underwent surgical intervention. The cases were randomly divided into Group 1 (n = 100; F 56, M 44) for surgeries with curettage and autogenous bone grafting, and Group 2 (n = 100; F 55, M 45) for surgeries with curettage and bone graft substitutes. The placebo control Group 3 consisted of cases operated by curettage only (n = 56; F 31, M 25). The follow-up period was set at 30 months. Results: The duration of surgery was 51 ± 4 min in Group 1 and 27 ± 1 min in Group 2 (p = 0.008). In Group 1, the rate of recurrence was 6% against 1% in Group 2 (p = 0.005). No other statistically significant differences in postsurgical outcomes between three involved groups were noted. Conclusion: In cases of enchondroma of the hand, postsurgical functional outcomes, the rate of postsurgical complications, the duration of immobilization, and the time to complete recovery are not influenced by the type of chosen grafting material. The implementation of HAp-collagen bone substitutes in granules instead of autogenous bone grafting reduces the duration of surgery. The implementation of autogenous bone grafting may increase the rate of tumor recurrence.en_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.subjectEnchondromaen_US
dc.subjectHanden_US
dc.subjectSurgeryen_US
dc.subjectBone graftingen_US
dc.subjectHAp-collagen bone substitutesen_US
dc.titleThe surgical management of the cavity and bone defects in enchondroma cases: A prospective randomized trialen_US
dc.typeArticleen_US
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