Please use this identifier to cite or link to this item: http://repository.tma.uz/xmlui/handle/1/11319
Title: TOShKENT ShAHRIDA 5- 11 YoShDAGI BOLALARDA COVID-19 INFEKSIYaSINING OLDINI OLIShDA BNT162B2 (Pfizer–BioNTech) VAKSINASINING SAMARADORLIGI
Authors: Matnazarova G.S., Xamzaeva N.T., Saidkasimova N.S., Kurbaniyazova M.O. Madenbayeva G.I
Keywords: COVID-19, SARS-CoV-2ga qarshi vaksina
Issue Date: 2024
Publisher: Ўзбекистон, Тошкент
Abstract: 2019 yilda boshlangan global COVID-19 pandemiyasi aholi salomatligi uchun xavfli tahdid bo‘ldi. Oxirgi o‘n yillikda uchta yangi betakoronavirus - ogir, o‘tkir respirator sindromi (SARS)-CoV, Yakin Shark; sindromi (MERS-CoV va SARS-CoV2 ko‘zgatuvchilari epidemiyani keltirib chiqarib, odamlar o‘rtasida o‘lim darajasini yukoriligi bilan ajralib turdi. Xozirgi kunda odam uchun virulent koronavirus (hCoVs) COVID-19 ni keltirib chiqaradigan SARSCoV2 hisoblanadi [1,3,9] PZR usuli virus RNK sini aniqlash buyicha yuqori sezgirlikka ega va COVID-19 ni erta davrlarida ishonchli tasdiklashi mumkin. Ogir, o‘tkir respirator sindrom (SARS) va Yakin Shark respirator sindromi (MERS) ni tekshirishlarning ko‘rsatishicha, kasallik belgilari paydo bulgandan 2 hafta o‘tib virusga karshi antitanacha 80- 100% bemorlarda aniqlanadi [2,5]. PZR usulida salbiy natija kayd etilganda va kasallik belgilari mavjud bo‘lmagan holda IgG va/yoki IgM antitanachani aniqlanishi COVID-19 pandemiyasi masshtabini anik baholashda serologik tekshirishlar muhim axamiyatga ega ekanligini yana bir tasdiklaydi [6,7]. Virusga karshi V-xujayraviy immunitet nafakat birlamchi yukishidan, balki kaytadan yukishidan ham himoya kilish uchun xizmat kiladi. Infeksiyadan organizm tozalangandan so‘ng, kasallikning o‘tkir va sog‘ayish boskichlarida paydo bo‘ladigan plazmatik xujayralar serologik xotirani chaqirib antitanacha ishlab chikishda davom etadi. Xozirgi vaqtda SARS-CoV-2 ga gumoral javob to‘liq o‘rganilmagan.
URI: http://repository.tma.uz/xmlui/handle/1/11319
Appears in Collections:Thesis, Articles

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