Please use this identifier to cite or link to this item: http://repository.tma.uz/xmlui/handle/1/1584
Title: Development of dermatological medicinal films technology of complex action
Authors: Nigmatjonov, Abdurashid
Tureeva, Galiya
Ishmukhamedova, Muattar
Sadykova, Nargiza
Rakhimova, Gulnora
Keywords: dermatological polymer films, methyluracil, chlorhexidine, chloramphenicol, filmforming polymer Na-CMC.
Issue Date: 13-Oct-2021
Publisher: Ташкент
Abstract: The article presents the results of research on the development of the optimal composition and technology of dermatological films of complex action, including those containing methyluracil, which stimulates regenerative processes, the antibacterial substance chloramphenicol, and chlorhexidine, which has an antiseptic effect. The nature of the interaction that occurs in the studied films between medicinal substances and a solution of the film-forming polymer Na-CMC has been studied. Using microbiological methods, the antibacterial activity of the recommended films was studied and it was found that they exhibit pronounced antimicrobial activity against: St. aureus, E. coli, Ps. aeruginosa, C. Albicans. Methods have been developed for the quantitative determination of the active substances of films of complex action by the method of high-performance liquid chromatography.
URI: http://repository.tma.uz/xmlui/handle/1/1584
ISSN: 1674-2974
Appears in Collections:Thesis, Articles

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Vol 48, No 10 2021 (2).pdfThe article presents the results of research on the development of the optimal composition and technology of dermatological films of complex action, including those containing methyluracil, which stimulates regenerative processes, the antibacterial substance chloramphenicol, and chlorhexidine, which has an antiseptic effect. The nature of the interaction that occurs in the studied films between medicinal substances and a solution of the film-forming polymer Na-CMC has been studied. Using microbiological methods, the antibacterial activity of the recommended films was studied and it was found that they exhibit pronounced antimicrobial activity against: St. aureus, E. coli, Ps. aeruginosa, C. Albicans. Methods have been developed for the quantitative determination of the active substances of films of complex action by the method of high-performance liquid chromatography.3.95 MBAdobe PDFView/Open


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