ИЗУЧЕНИЕ ИММУНОЛОГИЧЕСКИХ СВОЙСТВ РОТОВОЙ ЖИДКОСТИ У ДЕТЕЙ, БОЛЬНЫХ САХАРНЫМ ДИАБЕТОМ 1-ГО ТИПА

Abstract

mmunological study of oral fluid in children with type 1 diabetes mellitus. Material and methods: The study was conducted in 35 children aged 7-15 years with type 1 diabetes mellitus. The amount of immunoglobulins (IgG, IgA, slgA) and interleukin-6 in the oral fluid was determined. Results: Severe dysimmunoglobulinemia of IgG and IgA classes indicates a massive effect of various antigens on the body, including in the oral cavity in type 1 diabetes mellitus in children. A high content of the pro-inflammatory cytokine IL-6 in the oral fluid was revealed. Conclusions: The identified immunological disorders are most pronounced with a decrease in the compensation of the disease. Key words: diabetes, oral fluid, immunoglobulins, lysozyme, interleukins.