Comparative evaluation of the effectiveness of spironolactone and eplerenone in patients with chronic heart failure

Abstract

Chronic heart failure (CHF) is a pathophysiological condition in which the heart cannot meet the needs of tissue exchange due to impaired pumping function. According to the results of scientific research conducted in recent years, at least 26 million people are currently suffering from chronic heart failure. Despite the advances in modern medicine in the field of treatment and prevention, mortality and morbidity from this disease is still high. Statistical observations show that the number of patients with CHF will increase by 46% by 2030[2]. Prevention of such a negative growth creates the need for more in-depth research in the field of medicine.