Evaluation of the of clinical features of gout in female patients

Abstract

Abstract: To assess the clinical features of gout in female patients. The study included 40 patients with gout (20 men and 20 women), examined in 2022 in the department of rheumatology and cardio-rheumatology of the multidisciplinary clinic of the Tashkent Medical Academy. The main group consisted of women, the comparison group - men. The average age of women was 61.7±05.1 years, men - 59.9±8.6 years, disease duration was 5.2 years for women and 6.1 years for men. In the group of women, the median duration of the first attack of arthritis was 15 days, in the comparison group - 9 days (p=0.001). Chronic arthritis was in 70.1% of women and 29.9% of men (p<0.0001), its formation in women was faster. The median number of joints affected during the disease was 15 in women and 8 in men (p=0.0002). Tophi in women formed earlier than in men (median duration of the disease before their occurrence was 3.5 and 5 years, respectively; p=0.0002), their number was higher (median 6 and 3, respectively; p=0.002). Women were more likel y than men to have type 2 diabetes mellitus (DM) (p=0.02), chronic kidney disease (p<0.0001), higher serum cholesterol levels (p=0.02). Women more often than men took diuretics (61% versus 19%; p<0.0001), but less often consumed alcoholic beverages (63 and 31%, respectively; p<0.0001; 30 and 7%; p<0.0001). In women, gout is more severe; they are more likely than men to have type 2 diabetes, chronic kidney disease, higher cholesterol levels; Women are more likely than men to take diuretics and consume less alcohol.