The significance of biomarkers in joint damage in patients with reactive arthritis

Abstract

The study enrolled 120 patients in the age of 36,9±12,3 classified into three groups according to the trigger factors and 20 healthy subjects. On the basis of the obtained data about early stages of reactive arthritis (ReA) with Chlamydia trachomatis etiology, long- lasting progression, and particularly rise of cartilage oligomer matrix protein (COMP) in women we can make a conclusion about the initiation of early cartilage destruction in the structure of a joint. Besides that, it indicates activation of alteration in the articulate structure and development of secondary osteoarthritis in early stages of the disease.