INFLUENCE OF NON-STEROID ANTI-INFLAMMATORY DRUGS ON THE HEMOSTASIS SYSTEM IN PATIENTS WITH RHEUMATOID ARTHRITIS

Abstract

The greatest medical, social and economic burden on society is primarily associated with rheumatoid arthritis (RA). The desire to improve the quality of life of RA patients sometimes justifies lifelong prescription of nonsteroid anti-inflammatory drugs (NSAIDs). However, NSAIDs have a number of undesirable reactions, among which, in the last decade, complications from the cardiovascular system (CVS) have been given the greatest importance. Monitoring of the side effects of NSAIDs used in everyday practice is an urgent problem in modern medicine. This problem is especially relevant in rheumatic diseases, in which the systemic inflammatory process is associated with an increased risk of vascular accidents.