Lipid peroxidation as the main pathogenetic link in the development of liver failure

Abstract

IP addresses are a highly charged family of lipid-derived metabolites involved in signal transduction leading to activation of Akt, mTOR and calcium homeostasis; sphingosine-1-phosphate, sphingosine-1-phosphate, an ingolipid derived from ceramide, which are potent messenger molecules involved in the regulation of calcium mobilization, migration, adhesion, and proliferation; prostaglandins, which are derivatives of fatty acids.