Experience of using uperio in patients with chronic heart failure

Abstract

We examined 30 patients with coronary heart disease, angina pectoris FC III, the course of which was complicated development of CHF II-III Art. FC III (NYHA). In 19 patients in history large-focal myocardial infarction was detected, in 5 patients - left ventricular aneurysm, in 25 - arterial hypertension, in 11 - a permanent form of atrial fibrillation. The disease proceeded against the background of diabetes mellitus in 8 patients. Average age of patients was 60,4±1,7 years. All patients received for 2 months the drug Uperio 50 mg (valsartan 25,7 mg + sacubitril 24,3 mg) against the background of conventional CHF therapy, including ACE inhibitors, beta-blockers, diuretics and cardiac glycosides. Initially and after 2 months treatmentwith Uperio, all patients underwent a general clinical examination, ECG registration, Echocardiography, 6-minute walk test, assessment of quality of life and clinical condition