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http://repository.tma.uz/xmlui/handle/1/6136
Title: | Experimental substantiation of the use of hypoxia-inducible factor (hif-1α) for the development of toxic hepatitis. |
Authors: | Sayfutdinova Z.A., Karimov Kh.Y.,Saidov.A.B |
Keywords: | hypoxia-inducible factor; heliotrin intoxication; experimental toxic hepatitis; aryl hydrocarbon receptor transolator |
Issue Date: | Jan-2021 |
Publisher: | Cutting edge-science,Shawnee,USA Conference Proceedings |
Series/Report no.: | 83pp; |
Abstract: | This article provides an experimental rationale for the use of hypoxia-inducible factor (HIF-1α) for the development and course of toxic hepatitis based on heliotrin intoxication. Acute heliotrin intoxication was reproduced by a single subcutaneous administration of a sublethal dose of heliotrin to rats, prepared at the rate of 40 mg per 100 g of body weight. During the reproduction of experimental toxic hepatitis by the introduction of heliotrin, it was found that the HIF-1 content was on average 0.101667 ± 0.0022 ng / L. In blood plasma, the mean HIF-1 values were 0.2136 ± 0.0066 ng / L. |
URI: | http://repository.tma.uz/xmlui/handle/1/6136 |
ISBN: | 978-1-64945-242-9 |
Appears in Collections: | Thesis, Articles |
Files in This Item:
File | Description | Size | Format | |
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USA tezis.pdf | 579.75 kB | Adobe PDF | View/Open |
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