THE SIGNIFICANCE OF AMNIOCENTSIS IN THE PREVENTION OF CHROMOSOME-RELATED GENE DISEASES

Abstract

The purpose of the study: to determine the most effective type of tests used to detect a fetus with chromosomal disorders in the womb. Research materials and methods: the test results of 45 patients who submitted the amniocentesis test to the "Genotechnology" laboratory, 42 Kokcha Darvoza Street, Shaikhontohur District, were studied. We collected information about other methods of amniocentesis method (FISH) in Tashkent Medical Academy Multidisciplinary Clinic 14 - educational building. Analysis and discussion of the results: in 45 patients, the amniocentesis method made a very accurate diagnosis. In the analysis of the results, 10 out of 45 mothers (16-21 weeks pregnant, average age 35.3) gave birth to a child with Edwards syndrome, although they passed the test through maternal blood and received a healthy result. 20 mothers who donated blood 3 times did not provide complete information each time. The remaining 15 mothers had a false abortion, that is, the fetus was aborted even though it was healthy, or it was given information about its health, but it was born with Down's syndrome. Later, these expectant mothers resorted to the method of amniocentesis. 3 of these 45 pregnant mothers had Down's syndrome, 2 had Edward's syndrome, and it was left to the discretion of the family to have a medical abortion or save the child's life. The rest of the patients had healthy fetuses.