СЕМИЗЛИКНИ РИВОЖЛАНИШИ ВА УНИ БОШҚАРИЛИШИДА БИОЛОГИК ФАОЛ МОДДАЛАРНИНГ ТУТГАН ЎРНИ

Abstract

This review article presents literature data on the significance of the role of such factors as systemic inflammation, insulin resistance, expression of genes responsible for the development of fat cells, fatty acids, synthesis and breakdown of lipids, inflammatory and anti-inflammatory cytokines, adipokines, various hormones, as well as the relationship of receptors regulating the action biologically active substances, eating behavior and human appetite management. In this regard, identifying molecular-biological and genetic markers that are important in the course and development of the disease in the management of patients with obesity and metabolic syndrome is one of the urgent problems of modern medicine.