METHODS FOR ISOLATION OF COUMARINS FROM MEDICINAL PLANTS AND PLANT MATERIALS CONTAINING COUMARINS

Abstract

Relevance of the problem. It is important to study the biological properties of medicinal plants containing coumarins: anticoagulant, spasmolytic, capillary strengthening, venotonic and antitumor effects[1,2,3,4,5,6]. The purpose of the study. Studying the methods of extracting coumarins from plant materials. Materials and research methods. The following solvents are commonly used to separate coumarins from plant materials: ethyl and methyl alcohol. Using these solvents, we separate aglycones and coumarin glycosides. It is advisable to use 40- 70% ethyl alcohol to obtain glycosylated coumarins. Aglycones can be fully extracted using chloroform, diethyl ether, acetone, petroleum ether, and hexan