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DC Field | Value | Language |
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dc.contributor.author | Мирахмедова Хилола Тухтасиновна, Абдуллаев Улугбек Сайфуллаевич | - |
dc.date.accessioned | 2023-06-21T12:23:53Z | - |
dc.date.available | 2023-06-21T12:23:53Z | - |
dc.date.issued | 2023-05 | - |
dc.identifier.issn | 2181-7812 | - |
dc.identifier.uri | http://repository.tma.uz/xmlui/handle/1/8755 | - |
dc.description.abstract | There is evidence of an increased risk of atherosclerosis and cardiovascular disease (CVD) in in-flammatory rheumatic diseases. Psoriatic arthritis (PsA) is a seronegative spondyloarthropathy (SpA). Inflamma-tion in arthritis, as well as traditional risk factors for ath-erosclerosis, together with cytokines and adhesion mole-cules, influence the activation and dysfunction of the en-dothelium. Interleukin 17 (IL-17) and endothelin-1 (ET-1) activate and deregulate endothelial function and may increase the risk of atherosclerosis. Serum IL-17 and ET-1 are believed to be associated with the inflammatory process in PsA. In addition, IL-17 stimulates the produc-tion of fibrinogen by the liver and is also involved in the activation of endothelial dysfunction. | en_US |
dc.language.iso | other | en_US |
dc.publisher | Toshkent tibbiyot akademiyasi axborotnomas | en_US |
dc.subject | psoriatic arthritis, interleukin 17, endo-thelin-1, immunological disorders | en_US |
dc.title | Прогнозирование дисфункции эндотелия у больных псориатическим артритом | en_US |
dc.type | Article | en_US |
Appears in Collections: | Thesis, Articles |
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File | Description | Size | Format | |
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21_статья_Мирахмедова, Абдуллаев_У_С_Вестник_ТМА_№5_2023.pdf | 909.67 kB | Adobe PDF | View/Open |
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