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http://repository.tma.uz/xmlui/handle/1/5336| Title: | Prediction of COVID-19 manipulation by selective ACE inhibitory compounds of Potentilla reptant root: In silico study and ADMET profile |
| Authors: | Yuan Xu, Mahmood Al-Mualm, Ermias Mergia Terefe, Maksuda Ilyasovna Shamsutdinova, Maria Jade Catalan Opulencia, Fahad Alsaikhan, Abduladheem Turki Jalil, Ali Thaeer Hammid, Ayesheh Enayati, Hassan Mirzaei i, Vahid Khori i , Ali Jabbari i , Aref Salehi i, Alireza Soltani, Abdullah Mohamed |
| Keywords: | COVID-19; Potentilla reptans; Angiotensin II; |
| Issue Date: | 2022 |
| Publisher: | Arabian Journal of Chemistry |
| Series/Report no.: | УДК; |
| Abstract: | In the novel SARS-CoV-2 (COVID-19) as a global emergency event, the main reason of the cardiac injury from COVID-19 is angiotensin-converting enzyme 2 (ACE2) targeting in SARS- CoV-2 infection. The inhibition of ACE2 induces an increase in the angiotensin II (Ang II) and the angiotensin II receptor type 1 (AT1R) leading to impaired cardiac function or cardiac inflammatory |
| URI: | http://repository.tma.uz/xmlui/handle/1/5336 |
| Appears in Collections: | Thesis, Articles |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 1-s2.0-S1878535222002581-main.pdf | Prediction of COVID-19 manipulation by selective ACE inhibitory compounds of Potentilla reptant root: In silico study and ADMET profile | 1.91 MB | Adobe PDF | View/Open |
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