Features of Hemostasis in Women with MenstruaL-Ovarian Cycle Disorders Against the Background of COVID-19

Abstract

Abstract The study included 120 women with menstrual-ovarian cycle disorders against the background of COVID-19. According to the clinical course of COVID-19, all patients were divided into three groups. The first group consisted of 45 women (37.5%) with a mild form of COVID-19, the second group included 43 women (35.8%) with moderate COVID-19, and the third group comprised 32 women (26.7%) with severe COVID-19. The study results demonstrate a significant impact of COVID-19 on the hemostasis state in 92% of women with menstrual-ovarian function disorders against the background of COVID-19. The levels of fibrinogen are 1.8 times and D-dimer on average 2.0 times higher than in healthy women. A correlation has been established between the levels of D-dimer, fibrinogen, and the severity of the clinical course of COVID-19, specifically, the presence of a direct correlation of these indicators with the severe form of COVID-19.