Evaluation of the Relationship between Cardiac and Renal Fibrosis Markers in Different Hemodynamic Types of Chronic Heart Failure with and Without Anemia

Gadaev Abdigaffar Gadaevich, Khalilova Feruza Abdujalolovna, Akhmedov Khalmurad Sadullayevich

dc.contributor.author	Gadaev Abdigaffar Gadaevich, Khalilova Feruza Abdujalolovna, Akhmedov Khalmurad Sadullayevich
dc.date.accessioned	2021-12-28T08:36:39Z
dc.date.available	2021-12-28T08:36:39Z
dc.date.issued	2021
dc.identifier.issn	0033-3077
dc.identifier.uri	http://repository.tma.uz/xmlui/handle/1/1216
dc.description.abstract	Renal fibrosis markers were evaluated in dynamics to study specific changes in the kidneys of patients with different hemodynamic types and functional classes of chronic heart failure with anemia and to evaluate the effectiveness of complex treatment. The renal fibrosis marker TGF-β1 in the blood was 2591.0 ± 108.4 and 755.0 ± 18.87 pg / ml, respectively, in chronic heart failure with anemia and without anemia (p˂0.01). This was indicative of a fibrosis process occurring in the kidney. After complex treatments with the addition of iron, the TGF-β1 index decreased by 2.25 times (p ,0.01), the clinical condition, quality of life and resistance to physical exertion changed significantly positively.	en_US
dc.language.iso	en	en_US
dc.subject	chronic heart failure, chronic kidney disease, renal dysfunction, fibrosis markers, cystatin-C, TGF-β1, ferrokinetic indicators, galectin-3, hemodynamic types	en_US
dc.title	Evaluation of the Relationship between Cardiac and Renal Fibrosis Markers in Different Hemodynamic Types of Chronic Heart Failure with and Without Anemia	en_US
dc.type	Article	en_US