ROLE OF THE MONOOXYGENASE SYSTEM IN THE DEVELOPMENT OF ACUTE PANCREATITIS

Alimbekova, Lobarkhon; Sobirova, Rixsi; Tursunov, Djakhangir; Aslanova, Aziza

dc.contributor.author	Alimbekova, Lobarkhon
dc.contributor.author	Sobirova, Rixsi
dc.contributor.author	Tursunov, Djakhangir
dc.contributor.author	Aslanova, Aziza
dc.date.accessioned	2022-01-03T13:13:28Z
dc.date.available	2022-01-03T13:13:28Z
dc.date.issued	2021
dc.identifier.uri	http://repository.tma.uz/xmlui/handle/1/1426
dc.description.abstract	The article clarifies role of the monooxygenase system in the development of acute pancreatitis. Authors determine cytochrome P-450 possesses unique properties that ensure the maintenance of chemical homeostasis in physiological and pathological states of the internal organism medium. The liver is the main organ supporting physico-chemical homeostasis, detoxification of endogenously formed and exogenously introduced xenobiotics into the body. But there is also extrahepatic metabolism of foreign compounds. The intestine plays an important role in this process. Endogenous intoxication syndrome disrupts metabolism and reduces the functional activity of natural detoxification systems, in particular by inhibiting the liver’s monooxygenated detoxification system.	en_US
dc.language.iso	en	en_US
dc.publisher	Central Asian Journal of Medicine	en_US
dc.subject	monooxygenase system, homeostasis, cytochrome P-450, oxidative-reducing enzymes, endogenous intoxication, pathogenesis	en_US
dc.title	ROLE OF THE MONOOXYGENASE SYSTEM IN THE DEVELOPMENT OF ACUTE PANCREATITIS	en_US
dc.type	Article	en_US