IMPACT OF PROLONGED EXPOSURE OF PIRETROID PESTICIDES ON THE THYROID FUNCTION OF THE PREGNANT RATS AND THEIR OFFSPRING

Abstract

For two decades, the world's literature uses the term "endocrine-disrupting chemicals or endocrine disruptors” (EDC or ED), adopted by the Agency for the U.S. Environmental Protection Agency in 1991. This term combines all the chemicals that in the organism of humans and animals change the processes of synthesis, secretion, transport, and metabolism of natural hormones and thereby lead to a disruption of hormonal homeostasis. There are more than one hundred pesticides of which 80% are commonly used as insecticides and fungicides, have different endocrine-disrupting effects.