Оценка клинических особенностей ассоциированного артрита при при хроническом вирусном гепатите

Abstract

Chronic viral hepatitis remains relevant not only due to their prevalence, high frequency of chronicity and their severe complications, but also due to the presence of various extrahepatic manifestations. Extrahepatic manifestations are clinically manifested in approximately 40-70% of patients and may involve many organs. They mainly include articular disorders (arthritis or arthralgia), mixed cryoglobulinemia, small to medium vessel vasculitis, glomerulonephritis, lichen planus, B-cell lymphomas, and cutaneous porphyria. Currently, great importance is attached to the diagnosis of HCVaA. Non-invasive diagnostic methods are most effective for determining the early stage of the disease, so the formation of a target group at risk of developing HCVaA using reliable biomarkers of extrahepatic manifestations of hepatitis is a priority. ecently, the management of patients with HCVaA has been Actively studied. However, in our country, there are few scientific works devoted to the study of the prevalence, diagnosis and treatment of HCV-associated rheumatic manifestations. This work was aimed at assessing the frequency of detection of arthritis in patients infected with HCV (HCVaA), as well as to analyze the identified features of its manifestations using clinical research methods in this category of patients