Erap-1 and il-23r as a leading genetic predictors of development of ankylosing spondyloarthritis

Касимова М.Б., Ахмедова Н.А., Махаматходжаева Х.Б.. Шарапов З., Худойназаров А., Кадирова Ш.

dc.contributor.author	Касимова М.Б., Ахмедова Н.А., Махаматходжаева Х.Б.. Шарапов З., Худойназаров А., Кадирова Ш.
dc.date.accessioned	2022-10-11T07:51:20Z
dc.date.available	2022-10-11T07:51:20Z
dc.date.issued	2022
dc.identifier.uri	http://repository.tma.uz/xmlui/handle/1/2982
dc.description.abstract	A review of the genetic aspects of ankylosing spondylitis (AS), a chronic inflammatory disease of autoimmune origin with a predominant lesion of the axial skeleton is presented. Since the beginning of the era of genome-wide search for associations, more than 150 loci associated with AS have been identified, but this explains no more than 30% of cases of inheritance. The review attempts to understand the role of the ERAP1 genes in the development of AS. Continuation of research in this direction will create the prerequisites for the emergence of new goals for targeted therapy.	en_US
dc.language.iso	en	en_US
dc.publisher	Италия	en_US
dc.subject	ankylosing spondylitis, ERAP1, IL-23R, single nucleotide polymorphism, genetics.	en_US
dc.title	Erap-1 and il-23r as a leading genetic predictors of development of ankylosing spondyloarthritis	en_US
dc.type	Article	en_US