Predictive value of clinical and anamnestic risk factors for the development of high grades of genital proposition in women.

Abstract

Genital prolapse is a common disease in women with a multifactorial etiology. Pelvic floor dysfunction is likely contributed by the combinations of anatomical, physiological, genetic, lifestyle, and reproductive factors that interact throughout a woman's life. To assess the predictive value of the trigger factors for the development of genital prolapse about the formation of a high degree and severe course of genital prolapse in women. We studied 102 patients with violations of the architectonics of the pelvic organs. The exclusion criteria were pregnant and nulliparous women under 30 years of age. All patients underwent an assessment of the degree of genital prolapse using the international classifications POP-Q (Pelvic Organ Prolapse Quantification). The severity of manifestations of genital prolapse was assessed using the PFDI-20 questionnaire. The mean age of the study sample was 47.5 ± 13.6 years. According to logistic regression analysis, independent predictors of risk for the formation of a high degree and severe clinical course of genital prolapse in women are an increased body mass index, constipation, chronic lung disease, pelvic inflammatory disease, frequent labor, and delivery of large fetuses. Thus, timely identification and elimination of the most significant trigger risk factors for the development of genital prolapse in women will serve to predict and prevent a high degree and severe clinical and functional course of pelvic organ prolapse.