The role of Helicobacter Pylori in cardioesophageal cancer.

Abstract

Esophageal cancer ranks the eighth in the world’s cancer incidence and the sixth in the global cancer death cause. There are two major histological subtypes of the esophagus: esophageal squamous cell carcinoma (ESCC) and esophageal adenocarcinoma (EAC). ESCC and EAC have different geographic and demographic models. ESCC has a high incidence in many developing countries. The most important risk factors in Western countries are smoking and habitual consumption of alcohol. In developed countries such as North America, Australia, and Europe, esophageal adenocarcinoma has become the main subtype of esophageal cancer; its major risk factors include chronic gastroesophageal reflux disease, obesity, and smoking. Esophageal cancer is mainly a disease of the male population over 55 years of age.