dc.contributor.author |
Nodira I. Tursunova, Dilbar M. Almuradova, Khadicha Kh. Turayeva, Dilsora I. Mukimovaю |
|
dc.date.accessioned |
2022-10-12T14:10:41Z |
|
dc.date.available |
2022-10-12T14:10:41Z |
|
dc.date.issued |
2022 |
|
dc.identifier.uri |
http://repository.tma.uz/xmlui/handle/1/3801 |
|
dc.description.abstract |
Prevalence of germline BRCA mutations has been estimated to be about 1:1,600 women in the general population. Rate of BRCA1/2 mutations in Ashkenazi Jews population is 98-99%. Rate of BRCA1/2 mutations in Russian population is high – 28.4%. The average woman's lifetime risk of developing breast cancer is about 12%. In women with the BRCA1 mutation, the risk rises to about 72%, and in women with the BRCA2 mutation, to about 69%. They are also at a higher risk of getting cancer of a second breast after the first - the risk of developing contralateral breast cancer is about 40%. |
en_US |
dc.language.iso |
other |
en_US |
dc.publisher |
Other |
en_US |
dc.subject |
Hereditary breast and ovarian cancer , BRCA1/2 mutations, genetic test. |
en_US |
dc.title |
Hereditary breast and ovarian cancer |
en_US |
dc.type |
Article |
en_US |