| dc.contributor.author | Nodira I. Tursunova, Dilbar M. Almuradova, Khadicha Kh. Turayeva, Dilsora I. Mukimovaю | |
| dc.date.accessioned | 2022-10-12T14:10:41Z | |
| dc.date.available | 2022-10-12T14:10:41Z | |
| dc.date.issued | 2022 | |
| dc.identifier.uri | http://repository.tma.uz/xmlui/handle/1/3801 | |
| dc.description.abstract | Prevalence of germline BRCA mutations has been estimated to be about 1:1,600 women in the general population. Rate of BRCA1/2 mutations in Ashkenazi Jews population is 98-99%. Rate of BRCA1/2 mutations in Russian population is high – 28.4%. The average woman's lifetime risk of developing breast cancer is about 12%. In women with the BRCA1 mutation, the risk rises to about 72%, and in women with the BRCA2 mutation, to about 69%. They are also at a higher risk of getting cancer of a second breast after the first - the risk of developing contralateral breast cancer is about 40%. | en_US |
| dc.language.iso | other | en_US |
| dc.publisher | Other | en_US |
| dc.subject | Hereditary breast and ovarian cancer , BRCA1/2 mutations, genetic test. | en_US |
| dc.title | Hereditary breast and ovarian cancer | en_US |
| dc.type | Article | en_US |