RELATIONSHIP OF POLYMORPHISMS OF MTR GENE rs1805087, MTRR GENE rs1801394 TOHOMOCYSTEIN CONCENTRATION AND COVID-19 SEVERITY IN UZBEK PATIENTS.

Inoyatova, F K; Kurbonova, Z C; Babadjanova, S A

dc.contributor.author	Inoyatova, F K
dc.contributor.author	Kurbonova, Z C
dc.contributor.author	Babadjanova, S A
dc.date.accessioned	2022-12-02T10:59:43Z
dc.date.available	2022-12-02T10:59:43Z
dc.date.issued	2022-10
dc.identifier.issn	1303-5150
dc.identifier.uri	http://repository.tma.uz/xmlui/handle/1/4718
dc.description.abstract	One of the most severe complications of COVID-19 caused by SARS-CoV-2 infection is hypercoagulopathy-induced ischemic damage to vital organs, which causes many cases of disability and death in patients infected with COVID-19. Therefore, by thoroughly studying the factors that cause hypercoagulopathy, selecting patients who are prone to the development of this pathological process, and carrying out special proliferative and therapeutic procedures for them, it is possible to reduce the above-mentioned indicators of morbidity and mortality. One of the factors causing hypercoagulopathy is the polymorphisms of the MTR and MTRR genes, which are thrombophilic genes, and their study in Uzbek patients infected with COVID-19 helps to understand the correlation of different alleles of these genes with the amount of homocysteine in these studied patients, as well as their significancecan give in the pathogenesis of COVID-19.	en_US
dc.language.iso	en	en_US
dc.publisher	INDIA	en_US
dc.subject	MTR, MTRR, rs1805087, rs1801394 , wild allele, minor allele folate cycle, hyperhomocysteinemia, endothelial dysfunction.	en_US
dc.title	RELATIONSHIP OF POLYMORPHISMS OF MTR GENE rs1805087, MTRR GENE rs1801394 TOHOMOCYSTEIN CONCENTRATION AND COVID-19 SEVERITY IN UZBEK PATIENTS.	en_US
dc.title.alternative		en_US
dc.type	Article	en_US