Study of genotype frequency distribution polymorphic marker of T-786C of enos3 gene in diabetic nephropathy in patients with CD2 type

Jabbarov Ozimboy Otakhonovich, Karimov Hamid Yakubovich, Daminov Botir Turgunpulatovich, Boboev Kodirjon Tuhtaboevich

dc.contributor.author	Jabbarov Ozimboy Otakhonovich, Karimov Hamid Yakubovich, Daminov Botir Turgunpulatovich, Boboev Kodirjon Tuhtaboevich
dc.date.accessioned	2020-03-03T07:21:00Z
dc.date.available	2020-03-03T07:21:00Z
dc.date.issued	2019
dc.identifier.uri	http://repository.tma.uz/xmlui/handle/1/491
dc.description.abstract	This article presents the results of a study of 129 patients with 2-type diabetes and 110 healthy people to determine whether polymorphic markers T-786C of the ENOS3 gene are related to the development of diabetic nephropathy (DN). Patients in the main group: 65 patients with duration of disease up to 10 years, without diabetic nephropathy (33 patients) and with diabetic nephropathy (32 patients), 64 patients with diabetes lasting more than 10-20 years, without diabetic nephropathy (31 patients) and diabetic nephropathy (33 patients). Genotyping was performed by polymerase chain reaction method. The study showed that the association of Callele C and ENOS3 gene genotype play a role in the development of diabetic nephropathy in patients with type 2 diabetes mellitus in the studied Uzbek nation.	en_US
dc.language.iso	other	en_US
dc.publisher	Tashkent	en_US
dc.subject	Keywords: diabetic nephropathy, diabetes mellitus, nitrogen oxide synthase, endothelin-1, gene, polymorphism, allele, genotype.	en_US
dc.title	Study of genotype frequency distribution polymorphic marker of T-786C of enos3 gene in diabetic nephropathy in patients with CD2 type	en_US
dc.type	Article	en_US