INFLUENCE OF SLEEP DISTURBANCE ON COGNITIVE FUNCTIONS IN CHRONIC CEREBRAL ISCHEMIA AND ITS CORRECTION

Abstract

Chronic cerebral ischemia (CCI) accounts for almost 2/3 of cerebrovascular diseases and causes cognitive impairment. In our article, we studied the influence of sleep disorders on cognitive functions. Patients took the drug melatonin to correct sleep disorders. 63 patients with CCI were examined. The mean age of the patients was 58.5±1.4 years. Patients were divided into 6 groups depending on the presence of sleep disorders and the stage of CCI disease. Sleep disorders and cognitive impairment were assessed using special questionnaires; in addition, the cognitive evoked potentials of P300 were studied. With an increase in the stage of CCI, cognitive indicators worsened according to the scales and parameters of cognitive evoked potentials P300. In patients with sleep disorders, there was a tendency to worsen sleep parameters according to the Epworth scale with an increase in CCI. In patients with CCI, sleep disturbances worsen cognitive functions. When treated with melatonin in patients with CCI, both sleep disorders and cognitive impairment improved.