РЕГУЛЯЦИЯ АТФ-ЗАВИСИМОГО К+  КАНАЛ МИТОХОНДРИЙ ПЕЧЕНИ ПРИ ДЕЙСТВИЯ  ПОЛИФЕНОЛОВ

Abdullayeva, G.T.,; Abdullayeva, M.T.,; Asrarov, M.I; Kurbanova, M.A.

dc.contributor.author	Abdullayeva, G.T.,
dc.contributor.author	Abdullayeva, M.T.,
dc.contributor.author	Asrarov, M.I
dc.contributor.author	Kurbanova, M.A.
dc.date.accessioned	2023-01-13T07:26:37Z
dc.date.available	2023-01-13T07:26:37Z
dc.date.issued	2022
dc.identifier.issn	2181-7812
dc.identifier.uri	http://repository.tma.uz/xmlui/handle/1/5759
dc.description.abstract	Objective: To study the effect of polyphenols rutan, getazan and euphorbin on the mitotic K+ATP channel of rat liver. Materials and methods: Conductivity of ATP-dependent K+ channels (0.3-0.4 mg/ml) in rat liver mitochondria was determined by changes in optical density at a wavelength of 540 nm in 3-ml cells. Results: The influence of the polyphenols rutan, getazan and euphorbin on the mitotic K+ATP channel in rats was studied. The results showed that the polyphenols rutan, getasan, and euphorbin activated mitochondrial channels in rats. Conclusion: The polyphenols of rutan, getasan and euphorbin have the ability to activate the mito K+ATP channel, which means that in the future they can be used to develop new drugs for cardioprotection and hypoxia.	en_US
dc.language.iso	other	en_US
dc.publisher	Вестник ТМА №8	en_US
dc.relation.ispartofseries	UDK:577.121.7;
dc.subject	liver, mitoK+ ATF-chanal, dysfunction, rutan, getasan, euforbin, correction, mitochondria.	en_US
dc.subject	печень, мито К+ АТФ –канал, дисфункция, рутан, гетасан, эуфорбин, коррекция, митохондрии	en_US
dc.title	РЕГУЛЯЦИЯ АТФ-ЗАВИСИМОГО К+ КАНАЛ МИТОХОНДРИЙ ПЕЧЕНИ ПРИ ДЕЙСТВИЯ ПОЛИФЕНОЛОВ	en_US
dc.type	Article	en_US