Modern approaches to clinical and laboratory research in non-alcoholic fatty liver disease

Abstract

Non-alcoholic fatty liver disease (NAFLD) is a pathological change in liver tissue due to excessive deposition of fatty droplets in hepatocytes (liver cells). This condition is also called steatosis, or fatty degeneration. With this disease, it is important to start treatment on time, otherwise an inflammatory process may begin. In this case, they talk about the development of steatohepatitis, which can later progress to fibrosis, and then to cirrhosis of the liver. In this regard, the development of prognostic criteria for liver fibrosis in patients with NAFLD is of particular relevance for the subsequent identification of risk groups for the formation and progression of this condition and optimization of diagnostic and treatment algorithms.