Evaluation of the efficacy of adjuvant therapy after laparoscopic removal of ovarian follicular cysts

Abstract

90 women were under supervision. O f these, 60 patients (main group) taking Midian as adjuvant therapy in the postoperative period, and 30 patients with the same diagnosis, but refused adjuvant therapy. The results o f hormonal studies in patients with FCO before laparoscopic surgery showed a high level ofF SH - 14.7 ± 0.16 I U/ 1 and a low concentration o f L H- 7.8 ± 0.38 IU/I. The content o f E2 in the main group was also high - 137.6±12.11 pg/ml, and the level o f progesterone was also significantly lower than 1.4±0.09 ng/ntl (p<0.001). The results o f a hormonal study in patients 3 months after laparoscopic removal o f FCO during adjuvant therapy with a drug containing 3 mg o f drospirenone and 0.03 mg o f ethinyl estradiol showed a decrease in FSH to 10.4±0.16 IU/l and an increase in LH to 10.0± 0.46 IU/l (p<0.001), decrease in E2 in the group to 108.8±11.87pg/ml (p>0.05). The use o f Midiana® as adjuvant therapy in women after laparoscopic removal o f ovarian follicular cysts led to the restoration o f fertility by 4.1 times (in 85% o f women) and the prevention o f relapses by 2.4 times.