Determination of the maximum permissible concentrations of biological fertilizer under chronic exposure to experimental animals

Abstract

Purpose: determination of the maximum allowable concentrations of biological fertilizer in case of chronic exposure to experimental animals (on the example of the biological fertilizer “Ep malchami”). Methods: a chronic 4-month inhalation experiment was carried out. As tests reflecting the general condition of organs and systems in the toxicological experiment, integral indicators were used: general condition, animal behavior, body weight dynamics. Results: when studying the effect of the biological fertilizer "Er malchami" on the body of white rats with a chronic four-month exposure, it was found that the concentration of 483.3 mg/m3 is toxic, 48.6 mg/m3 can be considered a threshold and 9.76 mg/m3 is defined as inactive. Conclusions. Biofertilizer is intended for pre-sowing treatment of seeds and seedlings of vegetable, industrial crops, potatoes, roots of young seedlings of fruit trees, forest crops in order to accelerate plant growth, increase yield, improve its quality, and suppress phytopathogenic microflora. Production agricultural tests indicate the effectiveness of the use of "Er malchami", which requires the development of maximum permissible concentrations.