Hif-1 regulates the transition to anaerobic metabolism

Xashimova G.T., Muhammadiev X.G, Valijonova M, Xidoyatova M.

dc.contributor.author	Xashimova G.T., Muhammadiev X.G, Valijonova M, Xidoyatova M.
dc.date.accessioned	2023-05-28T07:55:28Z
dc.date.available	2023-05-28T07:55:28Z
dc.date.issued	2023-04
dc.identifier.uri	http://repository.tma.uz/xmlui/handle/1/8066
dc.description.abstract	HIF-1 is one of the main genes coordinating this shift by inducing various glycolytic enzymes and glucose transporters such as aldolase A and pyruvate kinase M, which help cells efficiently generate energy in a hypoxic environment. In addition to increasing the expression of these enzymes, HIF-1 reduces mitochondrial oxygen consumption by activating pyruvate dehydrogenase kinase I and stopping the citric acid cycle.	en_US
dc.language.iso	en	en_US
dc.publisher	KLINIK LABORATOR DIAGNOSTIKADA INNOVATSION TEXNOLOGIYALARDAN FOYDALANISH, MUAMMOLAR VA YECHIMLAR	en_US
dc.relation.ispartofseries	№2;
dc.subject	hypoxia; ischemia; hypoxia-inducible factor; homeostasis; anaerobic glycolysis; Krebs cycle.	en_US
dc.title	Hif-1 regulates the transition to anaerobic metabolism	en_US
dc.type	Thesis	en_US