Fluoride’s toxicity and its effects on the Central Nervous System

Худойбергенова Дилафруз Хамзаевна, Нарзиев Нурали Мухамедович, Аликулов Ихтиер Тиловкобилович

dc.contributor.author	Худойбергенова Дилафруз Хамзаевна, Нарзиев Нурали Мухамедович, Аликулов Ихтиер Тиловкобилович
dc.date.accessioned	2023-06-03T10:48:36Z
dc.date.available	2023-06-03T10:48:36Z
dc.date.issued	2023-03
dc.identifier.citation	Fluoride is a toxic nonmetal that occurs naturally in the environment. It is used in many industries so exposure to it goes unnoticed. Factors that are responsible for fluoride intake are toothpaste additives, tea, coffee, water, meat, shellfish, food supplements etc. It is widely used for the prevention of dental caries. There are a few fluoride-containing medications too. For example, voriconazole (oral antifungal medication). A typical dose of voriconazole provides 65 mg/day of fluoride. Long-term usage can lead to high fluoride concentrations in serum. World Health Organization (WHO) recommends fluoride concentration to be below 1.5 mg/l. But one of the most responsible factor for fluoride toxicity in the human body is water as there are many geographical places where the concentration of fluoride in water is very high and dangerous for long-term usage. Such places include Eastern parts of Africa like Kenya and Ethiopia and Southeast Asia. In India, 70 million people are exposed to elevated levels of fluoride. People in these areas suffer various health issues like fluorosis. The aim of this paper is to shed some light on fluoride’s toxic nature and its effects on the central nervous system, which helps in warning people about the harmful effects of fluoride- containing ‘daily intake products’ including food and water.	en_US
dc.identifier.issn	2795-7365
dc.identifier.uri	http://repository.tma.uz/xmlui/handle/1/8296
dc.description.abstract	Fluoride (F) is an element that occurs naturally on earth. Exposure to fluoride has negative effects on the human body and the intake mainly depends on what the person is consuming i.e. food, water, and air. Accumulation of fluoride occurs after continuous exposure to it as it can take 20 years or more to become evident and studies have shown that it affects various body parts including the renal, liver, and central nervous system.	en_US
dc.language.iso	en	en_US
dc.publisher	Eurasian Research Bulletin	en_US
dc.subject	fluoride, toxic, factor, water, exposure, central nervous system	en_US
dc.title	Fluoride’s toxicity and its effects on the Central Nervous System	en_US
dc.type	Article	en_US