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The clinical significance of anti-fibrillarin (u3-rnp) antibodies in systemic sclerosis

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dc.contributor.author Zaripov S.I. Abdurakhmanova N.M. Pulotova S.A.
dc.date.accessioned 2023-06-13T05:49:49Z
dc.date.available 2023-06-13T05:49:49Z
dc.date.issued 2023
dc.identifier.citation Тошкент en_US
dc.identifier.uri http://repository.tma.uz/xmlui/handle/1/8365
dc.description.abstract Systemic sclerosis is a chronic autoimmune connective tissue disease, characterized by endothelial dysfunction, immune abnormalities and progressive fibrosis of skin and multiple inner organs. The main marker of an abnormal immune response is circulating autoantibodies, which are found in more than 95% of patients with systemic sclerosis. It is important to study the clinical, immunological, diagnostic and prognostic significance of autoantibodies, especially anti-fibrillarin antibodies produced against the fibrillarin protein. en_US
dc.language.iso en en_US
dc.subject To study the clinical significance of anti-fibrillarin (U3-RNP) antibodies in systemic sclerosis. en_US
dc.title The clinical significance of anti-fibrillarin (u3-rnp) antibodies in systemic sclerosis en_US
dc.type Thesis en_US


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