"Post-traumatic immunosuppression and the possibility of their  correction"

Saloxiddinov Faxriddin Baxriddinovich, Hayitov Abdurasul Abdusattorovich, Xamrayev Alisher Shoxobovich, Tuguzov Bunyod Esonovich, Ismoilov Nurhon Uralovich, Mamajonov Shavkat Toxirovich

dc.contributor.author	Saloxiddinov Faxriddin Baxriddinovich, Hayitov Abdurasul Abdusattorovich, Xamrayev Alisher Shoxobovich, Tuguzov Bunyod Esonovich, Ismoilov Nurhon Uralovich, Mamajonov Shavkat Toxirovich
dc.date.accessioned	2024-01-15T18:56:08Z
dc.date.available	2024-01-15T18:56:08Z
dc.date.issued	2023-10
dc.identifier.issn	2181-0842
dc.identifier.uri	http://repository.tma.uz/xmlui/handle/1/10233
dc.description.abstract	Serum concentrations of soluble activation receptors (sCD25 and sCD 95), cytokines (IL-2, IL-6,and TNF-α) were studiedin the dynamics of traumatic disease treatment. Those submitted data points out the development of posttraumatic immunosuppression in the early stages of observation, such as neutrophilic leukocytosis, relative lymphopenia, increase of sCD25 and sCD95, cytokines IL-6 and TNF-α, reduction of IL-2, which are more pronounced in patients at risk of posttraumatic complications development. Basic therapy corrects only some parameters of immunity, but the usage of polyoxidonium entirely recover affected immunological indicators. It is recommended to include polyoxidonium into basic therapy in patients with traumatic disease at early stages.	en_US
dc.publisher	Science and education	en_US
dc.subject	traumatic disease, therapy, immunocorrection, polyoxidonium, soluble receptors, cytokines	en_US
dc.title	"Post-traumatic immunosuppression and the possibility of their correction"	en_US
dc.type	Article	en_US