Abstract:
Scientific research data on Covid-19 shows that 14-53% of patients have signs of mild-tomoderate liver damage: increased levels of aminotransferases, hypoproteinemia,
increased prothrombin time. Severity of Covid-19 cases are correlated with extensity of
liver damage. On the other hand, prior to infection, active liver disease increased the
severity of the infection. SARS-Cov-2 has a feature of direct damage of the hepatocytes
which is explained by presence of angiotensin converting enzyme 2 receptors in the
cholangiocytes. Patients with chronic diffuse and advanced liver diseases are at higher
risk of infection due to cirrhosis affect on immune mechanisms.
