The Role of Cartilage Oligomer Matrix Protein (COPM) in Diagnostics of Early Cartilage Destruction in Reactive Arthritis

Abstract

The study enrolled 120 patients in the age of 36,9±12,3 classified into three groups according to the trigger factors and 20 healthy subjects. On the basis of the obtained data about early stages of ReA with Chlamydia trachomatis etiology, long-lasting progression, and particularly rise ofcartilage oligomer matrix protein(COMP) in womenwe can make a conclusion about the initiation of early cartilage destruction in the structure of a joint. Besides that, it indicates activation of alteration in the articulate structure and development of secondary osteoarthritis in early stages of the disease