Abstract:
Purpose of the study. Analysis of the role of the gene-determinant of the PGC-1A(G/A) inflammation regulator in the pathogenesis and course of gastric ulcer
and duodenal ulcer.Materials and research methods. 100 patients with gastric and duodenal ulcer were examined. Of these,groups with complications (n = 49) and without it (n =51) were selected, which were examined for polymorphic variants of the PGC-1A(G/A) genes by PCR. Results. The PGC-1A(G/A) are markers of the development
of duodenal and gastric ulcer. Conclusion. Identification of candidate genes for
peptic ulcer disease provides prevention of this pathology and plays an important role in the development of new approaches to the diagnosis and treatment of peptic
ulcer disease.
