Allelic polymorphism of the il-1β (rs1143627) gene in patients with immune thrombocy th immune thrombocytopenia.

Hamid Y. Karimov , Dilfuza S. Matkarimova ,Kodirjon T. Boboev .

dc.contributor.author	Hamid Y. Karimov , Dilfuza S. Matkarimova ,Kodirjon T. Boboev .
dc.date.accessioned	2022-01-05T10:28:45Z
dc.date.available	2022-01-05T10:28:45Z
dc.date.issued	2021
dc.identifier.uri	http://repository.tma.uz/xmlui/handle/1/1577
dc.description.abstract	Purpose of the study. To study the features of the frequency distribution of alleles and genotypes of IL-1β (rs1143627) gene polymorphism, its role in the development of ITP in people of the Uzbek ethnic group. Material and methods: The study included 89 patients with ITP (median age - 41 ± 1.7 years) (main group) who were admitted for examination by the RSPMCH in the period from 2012 to 2018. Detection of IL-1β (rs1143627) polymorphism was carried out by SNP-PCR. Results and its discussion. Carriage of the IL-1β gene polymorphism (rs1143627) is not associated with the risk of developing immune thrombocytopenia.	en_US
dc.language.iso	en	en_US
dc.publisher	Central asian journal of medicine	en_US
dc.subject	immune thrombocytopenia, IL-1β (rs1143627) gene polymorphism, allele, genotype, association, risk of development.	en_US
dc.title	Allelic polymorphism of the il-1β (rs1143627) gene in patients with immune thrombocy th immune thrombocytopenia.	en_US
dc.type	Article	en_US