Abstract:
We examined 30 patients with coronary heart disease, angina pectoris FC III, the course of which was complicated development of CHF II-III Art. FC III (NYHA). In 19
patients in history large-focal myocardial infarction was detected, in 5 patients - left ventricular aneurysm, in 25 - arterial hypertension, in 11 - a permanent form of atrial fibrillation. The disease proceeded against the background of diabetes mellitus in 8 patients. Average age of patients was 60,4±1,7 years. All patients received for 2 months the drug Uperio 50 mg (valsartan 25,7 mg + sacubitril 24,3 mg) against the background of conventional CHF therapy, including ACE inhibitors, beta-blockers, diuretics and cardiac glycosides. Initially and after 2 months treatmentwith Uperio, all patients underwent a general clinical examination, ECG registration, Echocardiography, 6-minute walk test, assessment of quality of life and clinical condition
