Abstract:
The effect of the flavonoid
glycoside sophoraflavonoloside isolated from
the petals of the Crocus sativus L plant
(Saffron seed) on hepatoprotective, choleretic
and approximate motor activity in chronic
liver damage with heliotrin when
administered orally at a dose of 100 mg / kg
under experimental conditions was studied.
The results obtained on the basis of the
conducted studies were compared with the
control group and the most active dose of the
comparative drug Karsil at a dose of 50
mg/kg. Based on preliminary research results,
it was found that Soforaflavonoloside does
not lag behind karsil and even slightly
surpasses a comparable drug in
hepatoprotective and choleretic properties.
This suggests that the substance under study
requires a more extensive in-depth study of
the effect of sophoraflavonoloside on the
normal and impaired functioning of the liver.
