EFFECTS OF THE METABOLIC SYNDROME ON THE LEVEL OF PROINFLAMMATORY CYTOKINES (IL-1β AND IL-6) IN PATIENTS WITH OSTEOARTHRITIS

Abstract

This article summarizes the current understanding of the role of cytokines in the pathogenesis of osteoarthritis (OA). An imbalance between pro inflammatory and anti-inflammatory cytokines in the joint tissues contributes to the development of inflammation and cartilage damage, which leads to progressive joint degeneration. This research studied the role of pro-inflammatory cytokines in OA and the impact on the course of disease against the background of metabol ic syndrome.