Abstract:
This article discusses the course of pulmonary hypertension in chronic obstructive pulmonary disease, in particular the relationship between systolic pressure in the lungs and blood gases, as well as a comparative analysis of bosentan and sildenafil. The results of the study showed that in chronic obstructive pulmonary disease with pulmonary hypertension in stages II-III-IV of the disease, there are the following correlations in accordance with systolic pressure in the pulmonary artery, a positive relationship in the II degree with pCO2 (r = 0.3), (P < 0.03), negative pO2 (r = -0.3, P < 0.02), also grade III positive relationship with pC02 (r = 0.54, P < 0.001) and negative with pO2 and sO2 (r = -0.6, P < 0.001 and r = respectively).